讲座题目：Multiscale Investigation of Red Blood Cells: Model Development and Applications
讲座地点：腾讯会议 ID：726 563 123
报 告 人：Qiang Zhu教授（加利福尼亚大学圣迭戈分校）
Qiang Zhu got his PhD in applied mechanics from the Massachusetts Institute of Technology. He is currently a professor in the University of California San Diego. His research focuses on fluid-structure interaction problems in ocean engineering, bioinspired engineering, and biomedical research. His research lab homepage can be found: http://fessrg.ucsd.edu/
Erythrocytes, also known as red blood cells or RBCs, play important physiological roles in the transportation of oxygen and carbon dioxide around the body. These cells have a well-documented molecular architecture including a composite membrane and cytosol inside. We have developed a molecular-detailed model of the cell membrane based on a multiscale algorithm. This structural model is then combined with a Stokes-flow-based fluid dynamics model to study dynamics of RBCs in vivo or in vitro. With this model we have studied several canonical problems. In this talk I will focus on one of them, the vesiculation of RBCs, which is an important physiological procedure in the cell metabolism and aging process. I will show that based on model predictions we have developed a high-throughput experimental technique that is able to study this process in physiologically relevant conditions.