SCUT Research Team Armored Condensate Droplets with "Molecular Bodysuit"

The research team led by Prof. Jiang Lingxiang at SCUT published a study titled 'Universal Membranization of Synthetic Coacervates and Biomolecular Condensates Towards Ultrastability and Spontaneous Emulsification' in Nature Chemistry. The team developed Condensate-Amphiphilic Polymers (CAPs), which universally stabilize 'coacervate-water' interfaces and achieve ultrastability and spontaneous emulsification of synthetic coacervates and biomolecular condensates. CAPsmembranized droplets function as a 'molecular bodysuit' as they demonstrate exceptional stability not only in aqueous media but also under high-salinity, extreme pH, and organic solvent conditions.

This material shows promising applications in developing intelligent drug delivery systems and novel functional materials. Furthermore, it demonstrates potential for simulating cellular compartmentalization and molecular transport processes, providing innovative tools for research in artificial cell engineering, organelle biomimetics, and bioengineering applications.


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